Máster Universitario en Biotecnología y Bioingeniería

Dr. Pedro Zapater Hernández

Department: Instituto de Bioingeniería. Unit of Pharmacology and Clinical Trials.
Phone: + 34 96 591 3868
Email: zapater_ped@gva.es
Current Position: Clinical Pharmacologist. Unit of Clinical Pharmacology. Universitary General Hospital of Alicante.
Assistant Professor, Department of Pharmacology, Paediatrics and Organic Chemistry, School of Medicine, Universidad Miguel Hernández (Alicante, Spain).
Research Fields:

  1. Nervous and immune regulation of inflammatory process.
  2. Inflammation and stress in the pathogenesis of cancer.
  3. Use of drugs in special populations: cirrhosis, pancreatitis, inflammatory bowel disease.

Representative Publications:

  • Zapater P, Francés R, González-Navajas JM, de la Hoz MA, Moreu R, Pascual S, Monfort D, Montoliu S, Vila C, Escudero A, Torras X, Cirera I, Llanos L, Guarner-Argente C, Palazón JM, Carnicer F, Bellot P, Guarner C, Planas R, Solá R, Serra MA, Muñoz C, Pérez-Mateo M, Such J. Serum and ascitic fluid bacterial DNA: a new independent prognostic factor in noninfected patients with cirrhosis. Hepatology. 2008 Dec;48(6):1924-31.
  • Zapater P, Caño R, Llanos L, Ruiz-Alcaraz AJ, Pascual S, Barquero C, Moreu R, Bellot P, Horga JF, Muñoz C, Perez J, Garcia-Peñarrubia P, Perez-Mateo M, Such J, Frances R. Norfloxacin modulates the inflammatory response and directly affects neutrophils in patients with decompensated cirrhosis. Gastroenterology 2009; 137(5): 1669-79.
  • Zapater P, Gómez-Hurtado I, Peiró G, González-Navajas JM, García I, Giménez P, Moratalla A, Such J, Francés R. Beta-Adrenergic Receptor 1 Selective Antagonism Inhibits Norepinephrine-Mediated TNF-Alpha Downregulation in Experimental Liver Cirrhosis. PLoS One. 2012;7(8):e43371.
  • Zapater P, Llanos L, Barquero C, Bellot P, Pascual S, Carnicer F, Palazón JM, Gimenez P, Esteban A, Llorca L, Francés R, Horga JF, Such J. Acute effects of dipyrone on renal function in patients with cirrhosis: a randomized controlled trial. Basic Clin Pharmacol Toxicol. 2015 Mar;116(3):257-63.
  • Ortiz S, Zapater P, Estrada JL, Enriquez P, Rey M, Abad A, Such J, Lluis F, Francés R. Bacterial DNA translocation holds increased insulin resistance and systemic inflammatory levels in morbid obese patients. J Clin Endocrinol Metab. 2014 Jul;99(7):2575-83.








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